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Acute Ventilatory Failure in Lambert-Eaton Myasthenic Syndrome and Its Response to 3, 4-Diaminopyridine Neurol 46:1143-1145, Smith,A.&Wald,J., 1996 See this aricle in Pubmed Article Abstract Respiratory failure is a common manifestation of myasthenia gravis but is infrequent in Lambert-Eaton myasthenic syndrome(LEMS),where it is often related to the use of paralytic agents or intercurrent pulmonary pathology.Therapies that are effective acutely in myasthenia gravis are usually of minimal benefit in LEMS.We describe a patient with respiratory failure secondary to LEMS who responded to 3,4 diaminopyridine and review the 12 previously reported cases of ventilatory failure in LEMS.

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